The Casablanca wine valley is one of the area's newest wine regions, located about an hour outside of Santiago. Because of the ocean breezes from the Pacific, Casablanca became the first cool-climate wine producing region of Chile. Since the 1990s, the wines of this region have been distinguished by wine connoisseurs on merit of their aroma and flavor. Various wine tasting tours will acquaint you with the wines of the Casablanca region and, in addition to wine tasting, will give you insight into the production process. Depending on the organizer, tours cover anywhere between several hours and the entire day and include a wine tasting, lunch or dinner and transportation.

The oldest indigenous-owned and managed arts centre in Australia, the Tandanya National Aboriginal Cultural Institute features exhibitions of Aboriginal and Torres Strait Islanders art from across Australia.

Located in the heart of Santiago is Plaza de Armas, the centrepiece of the city. Initially, Santiago was designed around this central square in a grid pattern. A fountain in the middle of the square celebrates libertador (liberator) Simón Bolívar who emancipated Latin America from Spanish control. The historic centre of Santiago around Plaza de Armas is home to a variety of museums and impressive works of architecture that line several pedestrian precincts.

Ibrahim Palace is a notable example of Ottoman architecture, characterised by its historic fortification built with traditional materials such as mud and straw. The palace features a small museum showcasing Ottoman artefacts, as well as a mosque within its grounds.