Housed in a 15th century Franciscan monastery, this museum is truly stunning. On display is a wide range of Gothic artwork. The flagship piece of the museum is Hans Memling’s triptych "Last Judgement."

The Museum of Prehistoric Thera is located in Fira and showcases a great number of artefacts discovered on Santorini. The excavations started in the second half of the 17th century, and the museum today is home to a wide array of objects from the late Neolithic to the late Cycladic periods.

Venetian rule in Santorini extended from 1207 to 1580 and the last vestiges of this historical period live in the castles that dot the entire island. Five fortresses can be found in Santorini in Oia, Pyrgos, Emporio, Akrotiri, and Skaros, which have been partly demolished by the earthquakes that shook the island in the 15th and 16th centuries. Skaros is probably the most important and well-preserved among the five castles, built on the peak of the namesake rock to protect the village from pirate attacks. The ruins of the once magnificent fortress can be reached on foot from Agios Georgios church in Imerovigli, connected to Skaros by a 0,5km walking trail and a long stairway.

The Jefferson Memorial is located in the city's heart, just a few minutes walk from the White House. The monument has white Georgia marble steps and if you step inside, a Thomas Jefferson statue — by sculptor Rudulph Evans — unfolds in the middle.