Built on the land occupied earlier by the Corpus Christi hospital, one of the city's medieval hospitals. In 1558 the city exchanged plots with Archishop Esteban Almeyda and the hospital was relocated to the Parish of Santiago. The building may have started in the 16th Century, soon after the establishment of the Orihuela Bishopric. It underwent profound changes in the 18th Century under the reigns of Bishops José Flores Ososrio and Pedro Albornoa Tapia. In the mid-20th century, it lost its original functions, was restored at the beginning of the 21st Century and is currently home to the Diocese Museum of Sacred Art. At the back, facing the river, there is a gallery with semi-circular arches. Inside, another striking feature is the cloister with heraldic decoration, the main staircase of Alicante marble and the dome built on an octagonal base, with exterior cobalt blue glazed tiles.

Eugénie, the wife of Napoleon III, created Hôtel du Palais at the end of the 19th century, and it still towers over the northern end of Grand Plage. A visit is well worth the time. In fact, it is essentially a must-see – the interiors and the atmosphere are reminiscent of a bygone era.

The Casino Barrière is located just at the waterfront, so it allows for some amazing views of the ocean. It does not only offer a good time for those who like classic table games like Blackjack, Roulette, and Poker, but you can also come here and relax in their heated sea-water pool with an ocean view.

The Mondriaan House is the birth house of the famous Dutch painter Piet Mondriaan. The ground floor of the house details the development of the painter, the person, his art, and his life. On the first floor, you can visit temporary exhibitions of contemporary artists whose work reflects that of Mondriaan or who draw inspiration from his work.