Situated in the heart of the city, Palazzo Ducale has two distinct entrances, one from Piazza Matteotti and the other from Piazza De Ferrari, two of the city's most significant gathering places. Formerly the residence of the Doges of Genoa, this stunning Neoclassical building now serves as a museum and centre for cultural events and art exhibitions.

The Museum Kunstpalast, which was redesigned by Oswald Matthias Ungers and opened in 2001, is located in the centre of Düsseldorf, right on the Rhine river. Ever since it reopened, the house has gained a splendid international reputation with its high-quality exhibitions, such as Miró, Dalí, Warhol, Caravaggio, "Bonjour Russia", "Diana and Actaeon" and Per Kirkeby. The permanent exhibit too, whose spectrum ranges from medieval sculptures to an outstanding assortment of Baroque graphic works up to paintings of the Düsseldorf School of Painting and Expressionism, as well as contemporary photography, is held in great esteem all over the world. The Hentrich Glass Collection is also found in the Museum Kunstpalast, and is the most comprehensive glass collection in Europe, tracing the development of glass artistry without interruption from luxury glass objects of the pre-Roman period up to glass art from contemporary studios. The Robert Schumann Hall, a multifunctional hall offering a sophisticated program running from chamber music to cabaret, is also integrated into the museum.

At Teknikens Hus, visitors embark on an immersive journey into the realm of natural resources. This interactive science museum seamlessly merges education with entertainment, offering playful, hands-on exhibitions that encourage experimentation and exploration of technology. From the impactful industries of the North to the technology shaping everyday life. Additionally, daily shows in the digital planetarium treat visitors to celestial wonders, featuring stars and the enchanting Northern Lights.